2 responses

  1. trent
    January 30, 2010

    Data show about 132 minute average half-life for nicotine. Quicker for women and those taking estrogen and Birth COntrol pill with estrogen. Based on the half life and 14 days, your nicotine level will be 5.35E-49. In effect much less than you would get from 2nd hand smoke.
    The clearances of nicotine and cotinine, the clearance of nicotine to cotinine, and the trans-3′-hydroxycotinine/cotinine ratio were significantly higher in women than in men (nicotine clearance, 15.6 ± 4.3 mL · min−1 · kg−1 in men versus 18.8 ± 6.6 mL · min−1 · kg−1 in women; P < .001); they were also higher among women taking oral contraceptives than in those who were not taking oral contraceptives (nicotine clearance, 22.5 ± 6.6 mL · min−1 · kg−1 in women taking oral contraceptives versus 17.6 ± 6.1 mL · min−1 · kg−1 in those who were not; P < .05). Women who were menopausal or postmenopausal were not different from men. Among oral contraceptive users, nicotine metabolism was accelerated among those taking combined and estrogen-only contraceptives but not progesterone-only contraceptives.

  2. David F
    January 30, 2010

    The half life is 2 hours, according to wikipedia.
    So counting from your last intake, the amount you have left in your system is half as much as you did two hours previous.
    The real question is, what was your intake rate, and how much is in your system now? If you can answer either of those, you can calculate how much is left.

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